Article
BCL2-938C>A polymorphism and disease progression in chronic lymphocytic leukemia.
Leukemia & lymphoma - 1 Nov 2009
Zenz Thorsten, Benner Axel, Dührsen Ulrich, Dürig Jan, Döhner Hartmut, Siffert Winfried, Stilgenbauer Stephan, Nückel Holger
Abstract excerpt
A number of single nucleotide polymorphisms (SNP) have been implicated to impact upon the disease course of chronic lymphocytic leukemia (CLL). However, few of these association studies could be confirmed in independent studies in the past. Recently, three independent studies did not confirm the prognostic impact of a new functional SNP in the BCL2 gene (-938C>A) described by Nückel et al. For this reason we...
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