Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type.

Journal of human genetics - 1 Dec 2009

Okasaka Toshiki, Matsuo Keitaro, Suzuki Takeshi, Ito Hidemi, Hosono Satoyo, Kawase Takakazu, Watanabe Miki, Yatabe Yasushi, Hida Toyoaki, Mitsudomi Tetsuya, Tanaka Hideo, Yokoi Kohei, Tajima Kazuo

Abstract excerpt

Human 8-oxoguanine DNA glycosylase 1 (hOGG1) has a major role in the repair of 8-hydroxyguanine, a major promutagenic DNA lesion. The genetic polymorphism rs1052133, which leads to substitution of the amino acid at codon 326 from Ser to Cys, shows functional differences, namely a decrease in enzyme activity in hOGG1-Cys326. Although several studies have investigated the association between rs1052133 and lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Small Cell
Share to Carcinoma, Squamous Cell
Share to Cysteine
Share to DNA Glycosylases
Share to Meta-Analysis as Topic
Share to Multivariate Analysis
Share to Serine
Share to Smoking

Source

Identifiers

PMID: 19881468
DOI: 10.1038/jhg.2009.108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type.PMID 19881468Read ↗

Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

The hOGG1Ser326Cys polymorphism and increased lung cancer susceptibility in Caucasians: an updated meta-analysis.Semantic proximity Read ↗

Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk.Semantic proximity Read ↗

The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies.Semantic proximity Read ↗

Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.Semantic proximity Read ↗

The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

hOGG1 Ser326Cys polymorphism and G:C-to-T:A mutations: no evidence for a role in tobacco-related non small cell lung cancer.Semantic proximity Read ↗

Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis based on 22,475 subjects.Semantic proximity Read ↗

The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk.Semantic proximity Read ↗

hOGG1 Ser326Cys polymorphism and lung cancer susceptibility.Semantic proximity Read ↗

A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.