Article
Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2014
Yin Zong-Bao, Hua Rui-Xi, Li Jing-Hui, Sun Chuan, Zhu Jin-Hong, Su Xing, Ji Chao, Xiang Qun, Hua Zhu-Ming
Abstract excerpt
The human 8-oxoguanine DNA glycosylase (hOGG1) gene plays an important role in the repair of oxidatively damaged DNA base lesions and its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity and thus contributes to cancer susceptibility. Numerous studies have investigated the association between hOGG1 Ser326Cys polymorphism and lung cancer susceptibility; however, the conclusions are...
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