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Article

Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2002

Le Marchand Loïc, Donlon Timothy, Lum-Jones Annette, Seifried Ann, Wilkens Lynne R

Abstract excerpt

Oxidative stress may be one mechanism by which tobacco smoke causes lung cancer. A common oxidative damage to DNA is the highly mutagenic 7,8-dihydro-8-oxoguanine adduct, which can be repaired by 8-oxoguanine glycosylase I (OGG1). A Ser326Cys substitution polymorphism in the hOGG1 gene has been suggested, based on in vitro data, to reduce the activity of the enzyme. We tested the association of this polymorphism...

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Identifiers

PMID: 11927502

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.PMID 11927502Read ↗

hOGG1 Ser326Cys polymorphism and lung cancer susceptibility.Semantic proximity Read ↗

Smoking and hOGG1 Ser326Cys polymorphism contribute to lung cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

The hOGG1 Ser326Cys polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type.Semantic proximity Read ↗

hOGG1 Ser326Cys polymorphism and G:C-to-T:A mutations: no evidence for a role in tobacco-related non small cell lung cancer.Semantic proximity Read ↗

The hOGG1Ser326Cys polymorphism and increased lung cancer susceptibility in Caucasians: an updated meta-analysis.Semantic proximity Read ↗

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Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population.Semantic proximity Read ↗

The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk.Semantic proximity Read ↗

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