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Article

The hOGG1Ser326Cys polymorphism and increased lung cancer susceptibility in Caucasians: an updated meta-analysis.

Scientific reports - 1 Jan 2012

Zhong Dani, Li Guojian, Long Jianxiong, Wu Jizhou, Hu Yanling

Abstract excerpt

hOGG1 encodes a DNA repair enzyme responsible for the excision of reactive oxygen species (ROS) in damaged DNA. Previous studies have obtained inconsistent results. To validate the association between the hOGG1Ser326Cys polymorphism and lung cancer risk, we performed an updated meta-analysis of 20 studies (8739 cases and 10385 controls) using STATA version 11.1. With this approach, we tested the overall and...

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PMID: 22855704
DOI: 10.1038/srep00548
PMCID: PMC3409380

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