Article
Association analysis of PDE4B polymorphisms with schizophrenia and smooth pursuit eye movement abnormality in a Korean population.
General physiology and biophysics - 1 Jul 2015
Bae Joon Seol, Park Byung-Lae, Cheong Hyun Sub, Kim Jeong-Hyun, Kim Jason Yongha, Namgoong Suhg, Kim Ji-On, Park Chul Soo, Kim Bong-Jo, Lee Cheol-Soon, Kim Jae-Won, Choi Woo Hyuk, Shin Tae-Min, Hwang Jaeuk, Koh In Song, Shin Hyoung Doo, Woo Sung-Il
Abstract excerpt
Schizophrenia is a debilitating mental disorder with a high heritability rate. Located on chromosome 1p31.3, the human cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B) gene has been considered as an important candidate gene for the risk of schizophrenia. Several genetic association studies reported the association between PDE4B polymorphisms and the risk of schizophrenia in Caucasian, African American,...
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