Article
Peripheral blood and bone marrow immunophenotypic and functional modifications induced in acute leukemia patients treated with interleukin 2: evidence of in vivo lymphokine activated killer cell generation.
Cancer research - 1 Feb 1991
Foa R, Guarini A, Gillio Tos A, Cardona S, Fierro M T, Meloni G, Tosti S, Mandelli F, Gavosto F
Abstract excerpt
The effect of treatment with interleukin 2 (IL2) on the phenotypic and functional immune system of acute leukemia patients was investigated. Fifteen acute myeloid leukemia and acute lymphoid leukemia patients with evidence of persistent disease were further subdivided into two groups according to the percentage of bone marrow (BM) blasts: group a had 6-15% blasts and group b had 30-65%. Following two cycles of...
Topics
- Acute Disease
- Adolescent
- Adult
- Child
- Female
- Humans
- Immunophenotyping
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural