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Article

Interleukin-2-induced lymphoproliferative responses.

Cancer immunology, immunotherapy : CII - 1 Jan 1990

Winkelstein A, Weaver L D, Salva N, Machen L L

Abstract excerpt

Interleukin-2 (IL-2) is capable of both stimulating an in vitro lymphoproliferative response and augmenting non-major-histocompatibility-complex-(MHC)-restricted cytotoxicity. However, there are conflicting reports about the phenotypes of responding cells. In the present studies, we determined phenotypes of Ficoll/Hypaque-separated peripheral blood mononuclear cells stimulated with 50, 100 or 1000 U/ml IL-2;...

Topics

Antibodies, Monoclonal
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
CD56 Antigen
CD8 Antigens
Cell Division
Cells, Cultured
Dose-Response Relationship, Drug
Humans
Interleukin-2
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes

Phenotype

Receptors, Antigen, T-Cell

Receptors, Interleukin-2

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 1705176
DOI: 10.1007/BF01754207
PMCID: PMC11038427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1705176-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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