Article
Interleukin-2 activation of human bone marrow in long-term cultures: an effective strategy for purging and generation of anti-tumor cytotoxic effectors.
Bone marrow transplantation - 1 Feb 1994
Verma U N, Bagg A, Brown E, Mazumder A
Abstract excerpt
Our previous studies have shown that IL-2 activated bone marrow cells develop potent tumoricidal activity in vitro and in vivo. With the dual aim of in vitro purging and generation of effectors which could mediate graft-versus-leukemia effects in vivo, IL-2 activation of human bone marrow in long...
Topics
- Bone Marrow
- Bone Marrow Cells
- Bone Marrow Purging
- Bone Marrow Transplantation
- Cell Division
- Cells, Cultured
- Hematopoietic Stem Cells
- Humans
- Interleukin-2
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Lymphoma
- Melanoma
- Phenotype
- Time Factors
- Tumor Cells, Cultured