Article
Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms in Greek multiple sclerosis (MS) patients with bout-onset MS.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Jun 2010
Aggelakis Konstantinos, Zacharaki Fani, Dardiotis Efthimios, Xiromerisiou Georgia, Tsimourtou Vana, Ralli Styliani, Gkaraveli Maria, Bourpoulas Dimitris, Rodopoulou Paraskevi, Papadimitriou Alexandros, Hadjigeorgiou Georgios
Abstract excerpt
We investigated the association of specific polymorphisms of the interleukin IL-1b (AvaI -511 and TaqI +3,953) and IL-1 receptor antagonist (IL-1RN) (a variable number of tandem repeats; VNTR) genes with both the susceptibility to and the clinical characteristics in Greek multiple sclerosis (MS) patients cohort with bout-onset. Genotypes were determined from 351 patients with clinically definite MS and 375 age-...
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