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Article

Polymorphisms in genes encoding leptin, ghrelin and their receptors in German multiple sclerosis patients.

Molecular and cellular probes - 1 Jan 2000

Rey Linda K, Wieczorek Stefan, Akkad Denis A, Linker Ralf A, Chan Andrew, Hoffjan Sabine

Abstract excerpt

Multiple sclerosis (MS) is a neuro-inflammatory, autoimmune disease influenced by environmental and polygenic components. There is growing evidence that the peptide hormone leptin, known to regulate energy homeostasis, as well as its antagonist ghrelin play an important role in inflammatory processes in autoimmune diseases, including MS. Recently, single nucleotide polymorphisms (SNPs) in the genes encoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21664965
DOI: 10.1016/j.mcp.2011.05.004

Genes

GHSR
LEPR
GHRL
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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