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Article

Association of Interleukin-1 and Inteleukin-1 Receptor Antagonist Gene Polymorphisms with Multiple Sclerosis in Azeri Population of Iran.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2020

Asgharzadeh Mohammad, Jigheh Zahra A, Kafil Hossein S, Farhoudi Mehdi, Oskouei Daryoush S, Khaki-Khatibi Fatemeh, Fadaee Manouchehr, Vegari Ali, Asgharzadeh Vahid, Najafi-Ghalelou Nima, Poor Behroz M, Rashedi Jalil

Abstract excerpt

BACKGROUND: Cytokines as important mediators have a critical role in appropriate immune responses, the irregular production of which can lead to Multiple Sclerosis (MS). Proinflammatory cytokine interleukin-1 (IL-1) triggers inflammatory responses. Function and production of the cytokine are influenced by IL-1 coding gene polymorphism and those antagonists gene polymorphism. OBJECTIVE: The aim of the present...

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PMID: 32148206
DOI: 10.2174/1871530320666200309142541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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