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Article

Restricted virus replication in the spinal cords of nude mice infected with a Theiler's virus variant.

Journal of virology - 1 Feb 1991

Zurbriggen A, Yamada M, Thomas C, Fujinami R S

Abstract excerpt

The Daniels strain of Theiler's murine encephalomyelitis produces a chronic disease which is an animal model for human demyelinating disorders. Previously, we selected a neutralization-resistant virus variant producing an altered and diminished central nervous system disease in immunocompetent mice which was evident during the later stage of infection (after 4 weeks) (A. Zurbriggen and R. S. Fujinami, J. Virol....

Topics

Animals
Cell Line
Enterovirus Infections
Genetic Variation
Maus Elberfeld virus
Mice
Mice, Nude
Species Specificity
Spinal Cord
Virus Replication

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Identifiers

PMID: 1987366
DOI: 10.1128/JVI.65.2.1023-1030.1991
PMCID: PMC239852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1987366-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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