Article
Restricted virus replication in the spinal cords of nude mice infected with a Theiler's virus variant.
Journal of virology - 1 Feb 1991
Zurbriggen A, Yamada M, Thomas C, Fujinami R S
Abstract excerpt
The Daniels strain of Theiler's murine encephalomyelitis produces a chronic disease which is an animal model for human demyelinating disorders. Previously, we selected a neutralization-resistant virus variant producing an altered and diminished central nervous system disease in immunocompetent mice which was evident during the later stage of infection (after 4 weeks) (A. Zurbriggen and R. S. Fujinami, J. Virol....
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