Article
Chimeric Theiler's virus with altered tropism for the central nervous system.
Journal of virology - 1 May 1994
Jarousse N, Fiette L, Grant R A, Hogle J M, McAllister A, Michiels T, Aubert C, Tangy F, Brahic M, Peña Rossi C
Abstract excerpt
Theiler's virus is a neurotropic murine picornavirus which, depending on the strain, causes either an acute encephalitis or a persistent demyelinating disease. Following intracranial inoculation, the demyelinating strains infect sequentially the grey matter of the brain, the grey matter of the sp...
Topics
- Animals
- Base Sequence
- Capsid
- Capsid Proteins
- Central Nervous System
- DNA, Recombinant
- Mice
- Mice, Inbred BALB C
- Mice, Inbred Strains
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Phenotype
- Spinal Cord
- Theilovirus