Article
Luciferase Imaging of a Neurotropic Viral Infection in Intact Animals
11 Apr 2003
Abstract excerpt
The identification of viral determinants of virulence and host determinants of susceptibility to virus-induced disease is essential for understanding the pathogenesis of infection. Obtaining this information requires infecting large numbers of animals to assay amounts of virus in a variety of organs and to observe the onset and progression of disease. As an alternative approach, we have used a murine model of...
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