Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.

Nature genetics - 1 Jul 2009

Abstract excerpt

To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413 controls. We performed replication in an independent set of 2,256 cases and 2,310 controls, for a total of 3,874 cases and 5,723 controls. We identified risk-associated SNPs on chromosome 12q13-14 (rs703842, P = 5.4 x 10(-11); rs10876994, P = 2.7 x 10(-10);...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 20

Share to TYK2 gene

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Multiple Sclerosis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19525955
DOI: 10.1038/ng.396

Genes

EVI5
RPL5
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.PMID 19525955Read ↗

Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1.Semantic proximity Read ↗

Genome-wide significant association with seven novel multiple sclerosis risk loci.Semantic proximity Read ↗

Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.Semantic proximity Read ↗

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22Semantic proximity Read ↗

A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches.Semantic proximity Read ↗

Multiple sclerosis genetics.Semantic proximity Read ↗

Genome-wide association studies in multiple sclerosis: lessons and future prospects.Semantic proximity Read ↗

Meta-analysis of the Selected Genetic Variants in Immune-Related Genes and Multiple Sclerosis Risk.Semantic proximity Read ↗

Multiple susceptibility loci for multiple sclerosis.Semantic proximity Read ↗

Genetic Risk in Multiple Sclerosis: Susceptibility, Modifiers and Unresolved QuestionsSemantic proximity Read ↗

ANKRD55 and DHCR7 are novel multiple sclerosis risk loci.Semantic proximity Read ↗

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.