Article
EVI5 is a risk gene for multiple sclerosis.
Genes and immunity - 1 Jun 2008
Hoppenbrouwers I A, Aulchenko Y S, Ebers G C, Ramagopalan S V, Oostra B A, van Duijn C M, Hintzen R Q
Abstract excerpt
HLA-DRB1 is the major locus associated with risk for multiple sclerosis (MS). A recent genome-wide study showed three additional single-nucleotide polymorphisms (SNPs), within the IL2RA and IL7RA genes respectively, also to be associated with MS. Consistent association but lower significance was found for 13 other SNPs. In this study, we aimed to verify association of these SNPs with MS in 46 MS patients and 194...
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