Article
An ImmunoChip study of multiple sclerosis risk in African Americans.
Brain : a journal of neurology - 1 Jun 2015
Isobe Noriko, Madireddy Lohith, Khankhanian Pouya, Matsushita Takuya, Caillier Stacy J, Moré Jayaji M, Gourraud Pierre-Antoine, McCauley Jacob L, Beecham Ashley H, Piccio Laura, Herbert Joseph, Khan Omar, Cohen Jeffrey, Stone Lael, Santaniello Adam, Cree Bruce A C, Onengut-Gumuscu Suna, Rich Stephen S, Hauser Stephen L, Sawcer Stephen, Oksenberg Jorge R
Abstract excerpt
The aims of this study were: (i) to determine to what degree multiple sclerosis-associated loci discovered in European populations also influence susceptibility in African Americans; (ii) to assess the extent to which the unique linkage disequilibrium patterns in African Americans can contribute to localizing the functionally relevant regions or genes; and (iii) to search for novel African American multiple...
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