Effects of TCF7L2 polymorphisms on glucose values after a lifestyle intervention.

doi:10.3945/ajcn.2009.28379

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Article

Effects of TCF7L2 polymorphisms on glucose values after a lifestyle intervention.

The American journal of clinical nutrition - 1 Dec 2009

Bo Simona, Gambino Roberto, Ciccone Giovannino, Rosato Rosalba, Milanesio Nadia, Villois Paola, Pagano Gianfranco, Cassader Maurizio, Gentile Luigi, Durazzo Marilena, Cavallo-Perin Paolo

Abstract excerpt

BACKGROUND: TCF7L2 is the strongest locus linked to type 2 diabetes that has been identified thus far, and rs7903146 is the most significantly associated variant. Few intervention studies have shown that it has negative effects on metabolic improvement after lifestyle programs. OBJECTIVE: Our objective was to assess the effects of this variant on lifestyle intervention-induced changes in glucose values and...

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PMID: 19864407
DOI: 10.3945/ajcn.2009.28379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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