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Article

Association study of GATA-2 transcription factor gene (GATA2) polymorphism and Parkinson's disease.

Parkinsonism & related disorders - 1 May 2010

Kurzawski Mateusz, Białecka Monika, Sławek Jarosław, Kłodowska-Duda Gabriela, Droździk Marek

Abstract excerpt

It was shown that high levels of alpha-synuclein in substantia nigra are essential in pathogenesis of Parkinson disease (PD), and SNCA expression in neurons is controlled by GATA-2 transcription factor, which plays also crucial role in central nervous system development, and erythroid cells differentiation. Recently, significant association of two GATA2 SNPs with early-onset coronary artery disease has been...

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Source

Identifiers

PMID: 19864173
DOI: 10.1016/j.parkreldis.2009.10.006

Genes

GATA2
SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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