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Article

ATXN8 -62 G/A promoter polymorphism and risk of Taiwanese Parkinson's disease.

European journal of neurology - 1 Nov 2012

Chen I-C, Wu Y-R, Yang S-J, Kao S-H, Chen Y-C, Chang K-H, Lee C-M, Lee-Chen G-J, Chen C-M

Abstract excerpt

BACKGROUND AND PURPOSE: We recently reported a novel -62 G/A polymorphism within ataxin 8 (ATXN8) gene promoter region, with -62 G displaying significantly higher luciferase activity compared with -62 A. Phenotypic variability in spinocerebellar ataxia type 8 (SCA8) has been suggested, and large SCA8 repeats were found in patients with Parkinson's disease (PD). We aimed to investigate the association of ATXN8...

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Source

Identifiers

PMID: 22577844
DOI: 10.1111/j.1468-1331.2012.03749.x

Genes

ATXN8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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