Article
Genetic analysis of the NEUROG2 gene in patients with Parkinson's disease.
Neuroscience letters - 14 Jan 2010
Deng Sheng, Deng Hao, Le Weidong, Xu Hongbo, Yang Huarong, Deng Xiong, Lv Hongwei, Xie Wenjie, Zhu Shaihong, Jankovic Joseph
Abstract excerpt
The proneural protein Neurogenin 2 (NEUROG2) is a transcription factor of importance for the differentiation and survival of midbrain dopaminergic neurons. To determine whether genetic variation in the coding region of the NEUROG2 gene plays a role in the etiology of Parkinson's disease (PD), we screened DNA samples from 202 PD patients and 201 normal controls. No mutation in the NEUROG2 gene was identified in...
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