Article
NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach.
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2006
Healy Daniel G, Abou-Sleiman Patrick M, Ahmadi Kourosh R, Gandhi Sonia, Muqit Miratul M, Bhatia Kailash P, Quinn Niall P, Lees Andrew J, Holton Janice L, Revesz Tamas, Wood Nicholas W
Abstract excerpt
The NR4A2 gene, which may cause autosomal dominant Parkinson's disease (PD), has also been reported to be a susceptibility factor for sporadic PD. Here, we use a haplotype-tagging approach in 802 PD patients and 784 controls and demonstrate that common genetic variation, including NR4A2 haplotypes, does not influence the risk of PD in the Caucasian population.
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