Article
Novel GIGYF2 gene variants in patients with Parkinson's disease in Chinese population.
Neuroscience letters - 5 Apr 2010
Wang Lei, Guo Ji-feng, Zhang Wen-wen, Xu Qian, Zuo Xing, Shi Chang-he, Luo Lin-zi, Liu Jia, Hu Liang, Hu Ya-cen, She Lu, Jiang Hong, Yan Xin-xiang, Xia Kun, Pan Qian, Tang Bei-sha
Abstract excerpt
The Grb10-Interacting GYF Protein-2 gene (GIGYF2), located in the chromosomal region 2q36-q37, has been reported as a PARK11 gene with a causal role in familial Parkinson's disease (PD) in Italian and French populations. However, there is no comprehensive study of GIGYF2 gene conducted in Chinese patients with PD from mainland China. The 27 coding exons and intron/exon boundaries of the GIGYF2 gene were sequenced...
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