Article
Association study of semaphorin 5A with risk of Parkinson's disease in a Chinese Han population.
Brain research - 15 Dec 2008
Ding Haixia, Wang Feng, Ding Xinsheng, Song Xinjian, Lu Xiaowei, Zhang Kezhong, Xiao Hang, Ye Min, Chen Jiechun, Zhang Qingshan
Abstract excerpt
Parkinson's disease (PD) is a common neurodegenerative disorder with genetic risk factors. Semaphorin 5A (SEMA5A) was recognized as a risk factor for PD through high resolution whole genome association study by Maraganore et al. We used polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay to check two single nucleotide polymorphisms (SNPs) within SEMA5A in 340 PD patients and 222 PD...
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