Article
Angiotensin II type 2 receptor gene polymorphisms in cardiovascular disease.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2010
Balmforth Anthony J
Abstract excerpt
Considerable progress in our understanding of the role of the angiotensin II type 2 (AT(2)) receptor in the development of cardiac hypertrophy and coronary artery disease has been achieved using in vitro and in vivo animal models. Our understanding in humans, however, has been hindered by the lack of availability of specific AT(2) receptor agonists and antagonists suitable for human study. Nevertheless, an...
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