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Article

Epithelial-mesenchymal transition with expression of SNAI1-induced chemoresistance in colorectal cancer.

Biochemical and biophysical research communications - 18 Dec 2009

Hoshino Hiromitsu, Miyoshi Norikatsu, Nagai Ken-ichi, Tomimaru Yoshito, Nagano Hiroaki, Sekimoto Mitsugu, Doki Yuichiro, Mori Masaki, Ishii Hideshi

Abstract excerpt

BACKGROUND: Previous reports have demonstrated that SNAI1 plays a role in epithelial-mesenchymal transition (EMT) through the suppression of CDH1. Its role in the pathology and regulation of EMT expression to chemoresistance in colorectal cancer (CRC) has not yet been fully elucidated. METHODS: Immunohistochemistry was performed to evaluate the expression of Snai1 protein in 30 primary CRC samples. The biological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19861116
DOI: 10.1016/j.bbrc.2009.10.117

Genes

SNAI1
CDH1
VIM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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