Article
Epithelial-mesenchymal transition and somatic alteration in colorectal cancer with and without peritoneal carcinomatosis.
BioMed research international - 1 Jan 2014
Shelygin Y A, Pospekhova N I, Shubin V P, Kashnikov V N, Frolov S A, Sushkov O I, Achkasov S I, Tsukanov A S
Abstract excerpt
Colorectal cancer is highly metastatic even when the tumors are small. To disseminate, cells use a complex and multistage process known as the epithelial-mesenchymal transition, in which epithelial phenotype is transformed into mesenchymal phenotype. The objective of this study is to describe the epithelial-mesenchymal transition in terms of gene expression profile and somatic alterations in samples of colorectal...
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