Article
Signature sequence validation of human papillomavirus type 16 (HPV-16) in clinical specimens.
Journal of clinical pathology - 1 Mar 2010
Lee Sin Hang, Vigliotti Veronica S, Pappu Suri
Abstract excerpt
AIMS: Persistent infection indicated by detection of human papillomavirus 16 (HPV-16) on repeat testing over a period of time poses the greatest cervical cancer risk. However, variants of HPV-16, HPV-31 and HPV-33 may share several short sequence homologies in the hypervariable L1 gene commonly targeted for HPV genotyping. The purpose of this study was to introduce a robust laboratory procedure to validate HPV-16...
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