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Validation of human papillomavirus genotyping by signature DNA sequence analysis

22 May 2009

Abstract excerpt

BACKGROUND: Screening with combined cytologic and HPV testing has led to the highest number of excessive colposcopic referrals due to high false positive rates of the current HPV testing in the USA. How best to capitalize on the enhanced sensitivity of HPV DNA testing while minimizing false-positive results from its lower specificity is an important task for the clinical pathologists. METHODS: The HPV L1 gene DNA...

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PMID: 19463165
DOI: 10.1186/1472-6890-9-3

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