Article
Sequence variants of human papillomavirus type 16 in clinical samples permit verification and extension of epidemiological studies and construction of a phylogenetic tree.
Journal of clinical microbiology - 1 Sept 1991
Ho L, Chan S Y, Chow V, Chong T, Tay S K, Villa L L, Bernard H U
Abstract excerpt
Genomic variability between different viral isolates provides a powerful epidemiological tool for verifying ultrasensitive diagnostic procedures, understanding infectious pathways in individuals and human populations, and studying viral evolution. The potential of this approach has not yet been exploited for the diagnosis of human papillomaviruses (HPVs) like HPV type 16 (HPV-16), which are involved in genital...
Topics
- Base Sequence
- Cell Line, Transformed
- DNA, Viral
- Enhancer Elements, Genetic
- Epidemiologic Methods
- Female
- Genetic Variation
- Humans
- Molecular Sequence Data
- Papillomaviridae