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Article

Analysis of Human Papillomavirus Type 16 Variants Indicates Establishment of Persistent Infection

1 Sept 1995

Abstract excerpt

Sequence differences in the noncoding region of the human papillomavirus type 16 (HPV-16) genome were displayed using single-stranded conformational polymorphism (SSCP) analysis of polymerase chain reaction (PCR)-amplified material. Two variants accounted for 50%-70% of all HPV-16 variants from 3 cohorts in Seattle. Seventy subjects who were repeatedly HPV-16 DNA-positive over 2-8 4-monthly visits showed an...

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PMID: 7658068
DOI: 10.1093/infdis/172.3.747

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