Article
Detection of human papillomavirus type 16 DNA in consecutive genital samples does not always represent persistent infection as determined by molecular variant analysis.
Journal of clinical microbiology - 1 Sept 2000
Mayrand M H, Coutlée F, Hankins C, Lapointe N, Forest P, de Ladurantaye M, Roger M
Abstract excerpt
Persistent human papillomavirus (HPV) infection of the uterine cervix is a risk factor for progression to high-grade squamous intraepithelial lesions. Detection in consecutive genital samples of HPV-16 DNA, a frequently encountered HPV type, may represent persistent infection or reinfection. We undertook a study using PCR-single-strand conformation polymorphism (SSCP) analysis and sequencing of PCR products...
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