Article
Sequence variation of human papillomavirus type 31 long control region: phylogenetic and functional implications.
Journal of medical virology - 1 May 2013
Ferenczi Annamária, Gyöngyösi Eszter, Szalmás Anita, Hernádi Zoltán, Tóth Zoltán, Kónya József, Veress György
Abstract excerpt
About one-third of human papillomavirus (HPV) types infect the anogenital tract. High-risk genital HPV types (such as HPV 16, 18, 31, 33, and 35) are linked causally to the development of cervical cancer. The long control region (LCR) of the HPV genome regulates the replication and transcription of the viral genome. In this study, the functional significance of nucleotide sequence variation within the LCR of HPV...
Topics
- Adult
- Cervix Uteri
- Cluster Analysis
- DNA, Viral
- Female
- Gene Expression Profiling
- Genetic Variation
- Human papillomavirus 31
- Humans
- Hungary
- Middle Aged
- Molecular Sequence Data
- Phylogeny
- Regulatory Sequences, Nucleic Acid