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Article

The hOGG1 Ser326Cys polymorphism and Huntington's disease.

Toxicology - 5 Dec 2010

Coppedè Fabio, Migheli Francesca, Ceravolo Roberto, Bregant Elisa, Rocchi Anna, Petrozzi Lucia, Unti Elisa, Lonigro Renata, Siciliano Gabriele, Migliore Lucia

Abstract excerpt

Increasing evidence supports a role for oxidative DNA damage and impaired DNA repair mechanisms in the pathogenesis of age related neurodegenerative diseases. Within this context there is a current interest in the understanding of the role played by polymorphisms of DNA repair genes in the inter-...

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Source

Identifiers

PMID: 19857538
DOI: 10.1016/j.tox.2009.10.019

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19857538-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

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The hOGG1 Ser326Cys polymorphism and Huntington's disease.PMID 19857538Read ↗

The impact of single-nucleotide polymorphisms (SNPs) in OGG1 and XPC on the age at onset of Huntington disease.Semantic proximity Read ↗

Association of the hOGG1 Ser326Cys polymorphism with sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

The 8-oxoguanine DNA N-glycosylase 1 (hOGG1) Ser326Cys variant affects the susceptibility to Graves' disease.Semantic proximity Read ↗

DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.Semantic proximity Read ↗

hOGG1 SER326CYS genetic polymorphism in a Turkish population.Semantic proximity Read ↗

A Ser326Cys polymorphism in the DNA repair gene hOGG1 is not associated with sporadic Alzheimer's disease.Semantic proximity Read ↗

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup.Semantic proximity Read ↗

Genotype-phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies.Semantic proximity Read ↗

Identification and characterization of OGG1 mutations in patients with Alzheimer's disease.Semantic proximity Read ↗

Association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and age-related macular degeneration.Semantic proximity Read ↗

Associations between hOGG1 sequence variants and prostate cancer susceptibility.Semantic proximity Read ↗

Age at onset in Huntington's disease: replication study on the associations of ADORA2A, HAP1 and OGG1.Semantic proximity Read ↗

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