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Article

Associations between hOGG1 sequence variants and prostate cancer susceptibility.

Cancer research - 15 Apr 2002

Xu Jianfeng, Zheng Siqun L, Turner Aubrey, Isaacs Sarah D, Wiley Kathy E, Hawkins Gregory A, Chang Bao-li, Bleecker Eugene R, Walsh Patrick C, Meyers Deborah A, Isaacs William B

Abstract excerpt

8-Hydroxyguanine is a mutagenic base lesion produced by reactive oxygen species. The hOGG1 gene encodes a DNA glycosylase/AP lyase that can suppress the mutagenic effects of 8-hydroxyguanine by catalyzing its removal from oxidized DNA. A population-based (245 cases and 222 controls) and family-ba...

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PMID: 11956079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11956079-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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