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Article

A Ser326Cys polymorphism in the DNA repair gene hOGG1 is not associated with sporadic Alzheimer's disease.

Neuroscience letters - 13 Mar 2007

Coppedè Fabio, Mancuso Michelangelo, Lo Gerfo Annalisa, Manca Maria Laura, Petrozzi Lucia, Migliore Lucia, Siciliano Gabriele, Murri Luigi

Abstract excerpt

Oxidative damage accumulates in the DNA of the human brain over time, and is supposed to play a critical role in the pathogenesis of Alzheimer's disease (AD). It has been suggested that the brain in AD might be subjected to the double insult of increased oxidative stress, as well as deficiencies in repair mechanisms responsible for the removal of oxidized bases. The type of damage that is most likely to occur in...

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Identifiers

PMID: 17240059
DOI: 10.1016/j.neulet.2006.12.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A Ser326Cys polymorphism in the DNA repair gene hOGG1 is not associated with sporadic Alzheimer's disease.PMID 17240059Read ↗

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hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women.Semantic proximity Read ↗

Identification and characterization of OGG1 mutations in patients with Alzheimer's disease.Semantic proximity Read ↗

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