Article
Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Korea.
Journal of Korean medical science - 1 Oct 2001
Lee K W, Lee J M, Jung K S
Abstract excerpt
Pyrazinamide (PZA) is one of the most important drugs for the treatment of Mycobacterium tuberculosis infection. However, the increasing frequency of PZA-resistant strains limits its effectiveness. In Korea, most PZA-resistant strains also exhibit both isoniazid and rifampin resistance making it essential to identify these resistant strains accurately and rapidly for effective treatment of mycobacterial...
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