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Converting human pluripotent stem cells into β-cells: recent advances and future challenges

13 Jan 2010

Abstract excerpt

PURPOSE OF REVIEW: The transplantation of insulin-producing beta-cells derived from human embryonic stem cells and induced pluripotent stem cells (collectively termed pluripotent stem cells or PSCs) holds great promise for therapy of diabetes mellitus. The purpose of this review is to summarize recent advances in this area, emphasizing the importance of studies of endocrine pancreas development in efforts to...

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PMID: 19855279
DOI: 10.1097/mot.0b013e3283337e1c

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