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Pancreatic Beta Cell Differentiation From Human Pluripotent Stem Cells

7 Sept 2018

Abstract excerpt

Insulin-expressing beta cells are crucial for the maintenance of systemic glucose homeostasis. Elucidation of the molecular and cellular mechanisms of beta cell development, expansion, survival, and function are required for full understanding of the molecular pathogenesis of diabetes. However, access to human beta cells for such studies is limited by virtue of the logistics of acquisition, prior medical status...

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Share to Genetics and Neurodevelopmental Disorders
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PMID: 30192441
DOI: 10.1002/cphg.68

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