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Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?

19 Jan 2021

Abstract excerpt

Diabetes mellitus is a pandemic metabolic disorder that results from either the autoimmune destruction or the dysfunction of insulin-producing pancreatic beta cells. A promising cure is beta cell replacement through the transplantation of islets of Langerhans. However, donor shortage hinders the widespread implementation of this therapy. Human pluripotent stem cells, including embryonic stem cells and induced...

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PMID: 33477961
DOI: 10.3390/cells10010191

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