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Advances Toward Engineering Functionally Mature Human Pluripotent Stem Cell-Derived β Cells

9 Jul 2020

Abstract excerpt

Human stem cell-derived β (SC-β) cells have the potential to revolutionize diabetes treatment through disease modeling, drug screening, and cellular therapy. SC-β cells are likely to represent an early clinical translation of differentiated human pluripotent stem cells (hPSC). In 2014, two groups generated the first in vitro-differentiated glucose-responsive SC-β cells, but their functional maturation at the time...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 32733873
DOI: 10.3389/fbioe.2020.00786

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