Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Advances Toward Engineering Functionally Mature Human Pluripotent Stem Cell-Derived β Cells

9 Jul 2020

Abstract excerpt

Human stem cell-derived β (SC-β) cells have the potential to revolutionize diabetes treatment through disease modeling, drug screening, and cellular therapy. SC-β cells are likely to represent an early clinical translation of differentiated human pluripotent stem cells (hPSC). In 2014, two groups generated the first in vitro-differentiated glucose-responsive SC-β cells, but their functional maturation at the time...

Topics

Join the communities discussing this publication.

Pancreatic function and diabetes
Pluripotent Stem Cells Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32733873
DOI: 10.3389/fbioe.2020.00786

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Advances Toward Engineering Functionally Mature Human Pluripotent Stem Cell-Derived β CellsPMID 32733873Read ↗

An arduous journey from human pluripotent stem cells to functional pancreatic β cellsSemantic proximity Read ↗

Converting human pluripotent stem cells into β-cells: recent advances and future challengesSemantic proximity Read ↗

Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directionsSemantic proximity Read ↗

Concise Review: Pluripotent Stem Cell-Based Regenerative Applications for Failing β-Cell FunctionSemantic proximity Read ↗

Exploring optimal protocols for generating and preserving glucose-responsive insulin-secreting progenitor cells derived from human pluripotent stem cellsSemantic proximity Read ↗

Stepwise differentiation of functional pancreatic β cells from human pluripotent stem cellsSemantic proximity Read ↗

Towards a Functional Cure for Diabetes Using Stem Cell-Derived Beta Cells: Are We There Yet?Semantic proximity Read ↗

Manufacturing clinical‐grade human induced pluripotent stem cell‐derived beta cells for diabetes treatmentSemantic proximity Read ↗

How to make a functional β-cellSemantic proximity Read ↗

An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cellsSemantic proximity Read ↗

A perfect islet: reviewing recent protocol developments and proposing strategies for stem cell derived functional pancreatic isletsSemantic proximity Read ↗

Stem cell-derived pancreatic beta cells: a step closer to functional diabetes treatment?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.