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Article

Identification of genetic polymorphisms of human OAT1 and OAT2 genes and their relationship to hOAT2 expression in human liver.

Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2010

Shin Ho Jung, Lee Choong-Hee, Lee Sang Seop, Song Im-Sook, Shin Jae-Gook

Abstract excerpt

BACKGROUND: Organic anion transporters (OATs) play an essential role in the disposition of numerous organic anions. To clarify the interindividual variation in the function of OATs, genetic polymorphisms of the SLC22A6 and SLC22A7 in Korean subjects were investigated and associated with hepatic hOAT2 expression and the SLC22A7 genotype. METHODS: The genetic variants and their frequencies for the SLC22A6 and...

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PMID: 19854166
DOI: 10.1016/j.cca.2009.10.015

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