Article
Pharmacogenomics of the OATP and OAT families.
Pharmacogenomics - 1 Apr 2004
Marzolini Catia, Tirona Rommel G, Kim Richard B
Abstract excerpt
Drug disposition is highly dependent on the interplay between drug metabolism and transport in organs such as the intestine, kidney, and liver. Genetically determined variation in drug transporter function or expression is now increasingly recognized to have a significant role as a determinant of intersubject variability in drug response. Similar to the discoveries of functional genetic variations in drug efflux...
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