Article
Benznidazole alters the pattern of Cyclophosphamide-induced reactivation in experimental Trypanosoma cruzi-dependent lineage infection.
Acta tropica - 1 Feb 2010
Santos Daniela M, Martins Tassiane A F, Caldas Ivo S, Diniz Lívis F, Machado-Coelho George L L, Carneiro Cláudia M, Oliveira Riva de P, Talvani André, Lana Marta, Bahia Maria T
Abstract excerpt
The factors involved in the reactivation of chronic Chagas disease infection are not clear enough and may be related to host immune unbalance and/or parasite genetic diversity. To evaluate the role of the Trypanosoma cruzi genetic background in the Chagas disease reactivation, we inoculated Cyclophosphamide-immunosupressed (CyI) Swiss mice with clonal stocks from T. cruzi I (Cuica cl1, P209 cl1, Gamba cl1, SP104...
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