Article
Impact of dual infections on chemotherapeutic efficacy in BALB/c mice infected with major genotypes of Trypanosoma cruzi.
Antimicrobial agents and chemotherapy - 1 Sept 2007
Martins H R, Silva R Moreira, Valadares H M S, Toledo M J O, Veloso V M, Vitelli-Avelar D M, Carneiro C M, Machado-Coelho G L L, Bahia M T, Martins-Filho O A, Macedo A M, Lana M
Abstract excerpt
The aim of this work was to investigate the impact of dual infections with stocks of Trypanosoma cruzi major genotypes on benznidazole (BZ) treatment efficacy. For this purpose, T. cruzi stocks representative of the genetic T. cruzi lineages, displaying different susceptibilities to BZ, belonging to the major T. cruzi genotypes broadly dispersed in North and South America and important in Chagas' disease...
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