Article
Trypanosoma cruzi I and IV stocks from Brazilian Amazon are divergent in terms of biological and medical properties in mice.
PLoS neglected tropical diseases - 1 Jan 2013
Monteiro Wuelton Marcelo, Margioto Teston Ana Paula, Gruendling Ana Paula, dos Reis Daniele, Gomes Mônica Lúcia, de Araújo Silvana Marques, Bahia Maria Terezinha, Magalhães Laylah Kelre Costa, de Oliveira Guerra Jorge Augusto, Silveira Henrique, Toledo Max Jean de Ornelas, Vale Barbosa Maria das Graças
Abstract excerpt
BACKGROUND: In the Brazilian Amazon, clinical and epidemiological frameworks of Chagas disease are very dissimilar in relation to the endemic classical areas of transmission, possibly due to genetic and biological characteristics of the circulating Trypanosoma cruzi stocks. Twenty six T. cruzi stocks from Western Amazon Region attributed to the TcI and TcIV DTUs were comparatively studied in Swiss mice to test...
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