Article
Impact of Trypanosoma cruzi clonal evolution on its biological properties in mice.
Experimental parasitology - 1 Mar 2002
Toledo M J de O, de Lana M, Carneiro C M, Bahia M T, Machado-Coelho G L L, Veloso V M, Barnabé C, Tibayrenc M, Tafuri W L
Abstract excerpt
Twenty Trypanosoma cruzi stocks attributed to the 19, 20, 39, and 32 clonal genotypes were comparatively studied in BALB/c mice during the acute and chronic phases of the infection to test the working hypothesis that T. cruzi clonal structure has a major impact on its biological properties. Fourteen parameters were assayed: (1) infectivity; (2) prepatent period; (3) patent period; (4) maximum of parasitemia; (5)...
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