Article
Decreased intensity of inflammation in benznidazole-treated mice inoculated with Trypanosoma cruzi I stocks from Mexico and persistence of circulating parasites.
The American journal of tropical medicine and hygiene - 1 Oct 2012
Cruz-Zetina Guillermo, del Rio-Rodriguez Rodolfo, Ramos-Ligonio Angel, López Ruth, Monteon Victor
Abstract excerpt
We analyzed the intensity of inflammation and parasitism in BALB/c mice infected with Trypanosoma cruzi I stocks from Mexico with and without benznidazole treatment in the acute phase of disease. Heart and skeletal muscles were evaluated for parasites and inflammation and blood was evaluated for persistence of circulating parasites. Parasitemia was influenced by T. cruzi stocks used and benznidazole treatment....
Topics
- Animals
- Cardiomyopathies
- Chagas Disease
- Genotype
- Heart
- Inflammation
- Mexico
- Mice
- Mice, Inbred BALB C
- Muscle, Skeletal
- Nitroimidazoles
- Parasitemia
- Polymerase Chain Reaction