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Article

In utero smoke exposure and role of maternal and infant glutathione s-transferase genes on airway responsiveness and lung function in infancy.

American journal of respiratory and critical care medicine - 1 Jan 2010

Murdzoska Jasminka, Devadason Sunalene G, Khoo Siew-Kim, Landau Louis I, Young Sally, Goldblatt Jack, Zhang Guicheng, Le Souëf Peter N, Hayden Catherine M

Abstract excerpt

RATIONALE: Xenobiotics in the maternal circulation are capable of crossing the placental barrier so a reduction in the mother and fetus's detoxification ability due to genetic variation in the glutathione S-transferases (GSTs) could expose the fetus to higher levels of toxins. OBJECTIVES: To investigate the interactive effects of maternal smoking during pregnancy with maternal and infant GST genotypes on airway...

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Source

Identifiers

PMID: 19850945
DOI: 10.1164/rccm.200812-1887OC

Genes

GSTP1
GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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